The Toronto Maple Leafs are set to host the Florida Panthers in a critical Game 5 of the 2025 NHL playoffs conference semifinals on Wednesday. The reigning Stanley Cup champions, the Panthers, leveled the second-round series at two games apiece with a 2-0 victory over the Leafs in Game 4 on Sunday. The puck drops at 7 p.m. ET at Scotiabank Arena in Toronto, Ontario, Canada.
In the latest betting odds for the matchup, Florida is favored on the money line at -136 (wager $136 to win $100), while Toronto is the underdog at +115 (wager $100 to win $115). The total number of goals is set at over/under 6. The Panthers are also favored on the puck line at -1.5 with odds of +179. Analyzing predictions from a reliable sports modeling source is recommended before placing bets.
A respected sports projection model, known for simulating every NHL game 10,000 times, has shown strong performance in the 2025 NHL playoffs. Heading into the second week of the conference semifinals, it boasts a combined record of 79-55 on top-rated puck-line and over/under wagers, indicating positive returns for those who have followed its picks.
Based on this model`s analysis and the latest odds, here are some highlighted bets for the Maple Leafs vs. Panthers Game 5:
Toronto Maple Leafs +1.5 (-219)
This series has been characterized by close contests, with Games 1 through 3 each decided by a single goal. Furthermore, three of the five playoff games the Leafs have played on home ice have also ended with a one-goal difference. Game 4 remained a tight, one-goal affair until late in the third period. The projection model indicates a strong probability of the Maple Leafs covering the +1.5 puck line in Game 5.
William Nylander over 2.5 shots on goal (-140)
Leafs forward William Nylander has been an active shooter this postseason, surpassing the two-shot mark in four different playoff games, including four shots in Game 4. He has been productive with 15 points (six goals, nine assists) from 28 shots on goal during this playoff run and is expected to pose a significant offensive threat, particularly on home ice.
Aleksander Barkov over 2.5 shots on goal (+110)
Florida`s top-line center, Aleksander Barkov, has a history of success against Toronto. In the regular season, he recorded three points (one goal, two assists) and six shots in games against the Maple Leafs. More recently in the playoffs, he has demonstrated an ability to find shooting lanes against Toronto`s defense, registering four or more shots on goal in three of his last four appearances.
